Beta-blocker-like treatment for POTS
Treatments studied
Part of Brain & nervous system clinical trials.
This study tests whether a daily pill called mirabegron can help control the rapid heartbeat and other symptoms of postural orthostatic tachycardia syndrome (POTS). If you join, you'll take the study drug or a placebo for a set time and track your symptoms.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are 18 years or older.
- You have a confirmed POTS diagnosis, meaning your heart rate goes up by at least 30 beats per minute when you stand, and you've had symptoms for more than 3 months.
- You do not have a pacemaker and are not dependent on one.
- You are not pregnant or breastfeeding, and if you can become pregnant, you agree to use birth control.
- You can speak, read, and write in English.
- You are not currently taking certain medicines like codeine, digoxin, or flecainide, and you are not in another clinical trial.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
Similar studies
Other trials that look related to this one.
This study tests a new treatment (called aVNT) for people with POTS, a condition that causes a rapid heart rate when standing up. It aims to see if this treatment can help reduce symptoms and improve daily functioning.
This early-stage trial tests two medicines (guanfacine and cromolyn sodium) to see if they help with POTS symptoms like dizziness and rapid heartbeat. It's looking for people whose POTS started recently after a trigger and who may have signs of allergic-type reactions.
This study tests simple body movements (like squeezing your legs or squatting) to see if they help control POTS symptoms. It may offer a non-drug way to manage dizziness and fast heart rate when standing.
This study looks at how gut hormones control blood flow after eating in people with POTS. It may help explain symptoms like dizziness and rapid heartbeat after meals.
This study tests if a gentle electrical stimulation near the ear (called tragus stimulation) can help with POTS symptoms, like dizziness and rapid heartbeat when standing. It aims to see if this non-invasive method can improve your daily life.
This trial studies people with POTS (a condition where heart rate rises when you stand) and compares them with people without POTS. It tests body “adrenergic” (stress-chemistry) signals and how the body handles posture, which may help researchers find better ways to manage POTS.
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