Beta-3 therapy to help POTS symptoms
Treatments studied
Part of Brain & nervous system clinical trials.
This trial tests a new medication (mirabegron) to help people with POTS (postural orthostatic tachycardia syndrome)—a condition where your heart races and you feel dizzy when standing up. The drug works by activating a specific nerve pathway to help control your heart rate and blood pressure.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You have been diagnosed with POTS for at least 3 months, with symptoms like dizziness when standing and a heart rate increase of 30+ beats per minute
- You are 18 years or older
- You do not have a pacemaker that controls your heartbeat
- Your blood pressure is not severely high (under 180/110 mmHg)
- You have not taken any experimental medications in the past 4 weeks and are not in another clinical trial
- You are not pregnant or breastfeeding, and you can read and write English
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
Similar studies
Other trials that look related to this one.
This trial tests two medications—guanfacine and cromolyn sodium—to see if they can help people with POTS who have symptoms that started after a specific trigger. It might help if you have not found relief from other treatments.
This pilot study tests a treatment called aVNT for people with POTS. It aims to see if this treatment can help with symptoms like rapid heartbeat when standing up.
This study tests simple body movements (like squeezing your legs or squatting) to see if they help control POTS symptoms. It may offer a non-drug way to manage dizziness and fast heart rate when standing.
This study tests a non-invasive device that stimulates a nerve near your ear (called the tragus) to see if it can help manage POTS symptoms. It may be an option for people whose POTS has lasted more than 6 months and who do not have other serious health conditions.
This trial tests a gentle, non-invasive treatment for Postural Orthostatic Tachycardia Syndrome (POTS), a condition that causes a rapid heart rate when standing. It combines mild ear nerve stimulation with slow, paced breathing to see if it helps manage symptoms like dizziness and fatigue.
This study looks at how gut hormones control blood flow after eating in people with POTS. It may help explain symptoms like dizziness and rapid heartbeat after meals.
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