Early heart pump implant for shock after a heart attack
Treatments studied
Part of Heart & circulation clinical trials.
This trial studies whether putting in a small heart pump early (through the leg) helps people with a heart attack complicated by severe heart weakness (“cardiogenic shock”) compared with standard treatment. It aims to improve survival and recovery by supporting blood flow sooner.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You’re 18 to 80 years old
- Your heart attack/acute coronary syndrome started within the last 24 hours (up to 24 hours)
- You have cardiogenic shock, shown by very low blood pressure and/or needing medicines to keep it up, plus low heart pumping numbers
- There are signs your left heart is under strain and that organs are not getting enough blood (examples include very high BNP/NT-proBNP, high lactate, low urine output, or cold skin)
- You plan to have the blocked artery treated with PCI (a catheter procedure) after angiography
- A doctor believes there’s no major blockage preventing placement of a 14 French catheter in the groin (femoral artery), and you can/your family can give consent (or it can be done as an emergency consent process)
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
Similar studies
Other trials that look related to this one.
This study compares two support devices (Impella vs. IABP) for people with cardiogenic shock who are already on ECMO. It looks at how well the left side of the heart recovers when one of these devices is added.
This trial tests a new heart pump (Impella device) for people who have a severe heart attack and go into shock (very low blood pressure). It aims to see if the pump can help the heart recover better than standard care.
This trial tests whether using a temporary heart pump plus close monitoring improves recovery in people with severe heart failure after a heart attack, compared to standard care.
This trial tests if starting and adjusting heart failure medications with the help of an Impella 5.5 heart pump can improve recovery for people in cardiogenic shock. It focuses on those who are not on enough guideline-directed medications.
This trial is testing a temporary heart pump device that helps your heart pump blood when it's too weak to do its job. It's for people who have severe heart failure (cardiogenic shock) despite getting powerful medications to keep their heart working.
This study examines detailed data from patients who received an Impella 5.5 heart pump to treat cardiogenic shock—a life-threatening condition where the heart cannot pump enough blood. Researchers use advanced computer analysis to understand what helps patients recover best.
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