Early heart pump implant for shock after a heart attack
Treatments studied
Part of Heart & circulation clinical trials.
This trial studies whether putting in a small heart pump early (through the leg) helps people with a heart attack complicated by severe heart weakness (“cardiogenic shock”) compared with standard treatment. It aims to improve survival and recovery by supporting blood flow sooner.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You’re 18 to 80 years old
- Your heart attack/acute coronary syndrome started within the last 24 hours (up to 24 hours)
- You have cardiogenic shock, shown by very low blood pressure and/or needing medicines to keep it up, plus low heart pumping numbers
- There are signs your left heart is under strain and that organs are not getting enough blood (examples include very high BNP/NT-proBNP, high lactate, low urine output, or cold skin)
- You plan to have the blocked artery treated with PCI (a catheter procedure) after angiography
- A doctor believes there’s no major blockage preventing placement of a 14 French catheter in the groin (femoral artery), and you can/your family can give consent (or it can be done as an emergency consent process)
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
Similar studies
Other trials that look related to this one.
This study compares two support devices (Impella vs. IABP) for people with cardiogenic shock who are already on ECMO. It looks at how well the left side of the heart recovers when one of these devices is added.
This study looks at when to insert a small heart pump (Impella CP) in people who have had a heart attack and are in cardiogenic shock, a condition where the heart can't pump enough blood. The goal is to find out if placing the pump before or after the artery-opening procedure improves outcomes.
This trial is testing whether a temporary heart pump (Impella) can help people with severe heart failure and cardiogenic shock (when the heart can't pump enough blood). The goal is to see if this device can reduce fluid buildup and improve blood flow, but it's for people who are very ill and need extra support.
This trial tests whether using a small mechanical pump inside the heart plus careful monitoring with a special catheter can help people in shock after a heart attack. It compares this approach to standard care, aiming to improve survival and recovery.
This study tests whether a special heart pump (Impella 5.5) can help patients with severe heart failure (cardiogenic shock) safely start and increase their heart failure medications. The goal is to see if this approach can help the heart recover and improve outcomes.
This trial tests a new heart pump device (CorVad) to support the heart in people who are in cardiogenic shock after a heart attack. It may help stabilize blood pressure and improve blood flow, potentially giving the heart time to recover.
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