Pre-surgery chemotherapy and radiation for esophagus cancer
Part of Cancer, Digestive system clinical trials.
This study tests a new pre-surgery treatment plan that combines chemotherapy with focused, shorter-course radiation for esophagus or stomach-where-it-meets-the-esophagus (GEJ) adenocarcinoma. The goal is to shrink the tumor before surgery and improve treatment outcomes.
Summary written for real people, not researchers, by Clin2.
Who can take part
- Your cancer must be confirmed by biopsy as invasive adenocarcinoma in the esophagus or GEJ
- The cancer should be operable (not spread to other organs) and match certain tumor staging patterns
- Tumor size on scans must be within set limits (up to 8 cm long and 5 cm wide)
- You must be healthy enough for treatment, including blood counts, kidney, liver, and lung function targets
- You should be able to start radiation within 30 days of signing consent, and be age 18–80
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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