Test effects of VA-ECMO on the heart during cardiogenic shock
Part of Heart & circulation clinical trials.
This study looks at how a heart-support machine called VA-ECMO affects heart function in people with cardiogenic shock caused by a sudden heart artery problem. Your care team may use standard VA-ECMO, and the study will measure the heart’s response to support.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are age 18 to 75.
- You have cardiogenic shock from an acute coronary syndrome (sudden heart artery blockage/heart attack) confirmed during this hospital stay.
- Your treating team decides you need VA-ECMO (a heart-lung support machine that takes over breathing and circulation) for your current shock.
- At the time you join, your blood pressure (MAP) is above 65 and you are on fewer than 3 vasopressors/inotropes (blood pressure/heart-strength medicines).
- You do NOT have cardiogenic shock from sepsis, blood clot in the lungs (pulmonary embolism), COVID-19–related lung/heart failure, or severe right-heart failure from severe lung pressure problems.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
Similar studies
Other trials that look related to this one.
This trial studies whether using a life-support machine called ECMO (extra support for the heart and lungs) helps people who develop shock right after a heart attack. It aims to improve outcomes when blood flow is failing and organs may be struggling.
This trial tests if unloading the heart during ECMO support helps patients recover better from cardiogenic shock. It compares different ways to reduce the heart's workload.
This study will look at whether “left ventricular unloading” (using a device like IABP or Impella) helps people who are in cardiogenic shock while on VA ECMO. It compares outcomes for people who get unloading versus those who stay on VA ECMO alone.
This study looks at the best way to reopen blocked heart arteries (using a stent procedure) in people who had a heart attack complicated by severe shock and need a life-support machine called VA-ECMO. It may help improve outcomes by testing which revascularization approach works best for multi-vessel blockages.
This trial is studying whether using less of the medicines that raise blood pressure (vasopressors) can help people with severe heart failure who are on a heart-lung machine (ECMO) survive. It may answer if a gentler approach is safer.
This study is a registry that collects information from adults who need a temporary heart circulation support device such as VA-ECMO or an Impella pump (or newer similar devices). It may help doctors better understand which patients benefit most and how these devices are used in real life.
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