Brain stimulation study for major depression symptoms
Part of Mental health clinical trials.
This trial studies a way to change how excitable the brain is (through in-person brain stimulation) in people with major depression. It may help understand new treatments or symptom patterns that could be useful for major depression.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You have been diagnosed with major depression (major depressive disorder/major depressive episode).
- You do not have a moderate-to-severe risk of suicide.
- You do not have a past history of bipolar disorder or a psychotic disorder.
- You do not have substance use problems (alcohol or other substances).
- You are not pregnant and not breastfeeding.
- You do not have brain/electrical/metal implants (or a history of epilepsy) and no uncontrolled serious medical illness.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
Similar studies
Other trials that look related to this one.
This trial tests if deep brain stimulation (a device that sends tiny electrical pulses to mood-related brain areas) can help people with tough-to-treat depression. It uses brain-signal monitoring to see which patterns predict improvement.
This study uses an invasive approach (placement of brain monitoring/stimulation) to better understand how the brain processes reward in depression. It may help researchers develop more targeted treatments in the future.
This study tests whether an “accelerated intermittent theta-burst” brain stimulation treatment can improve major depressive disorder by affecting brain signaling pathways. You may be a candidate if you have moderate-to-severe depression and can safely undergo brain MRI.
This trial tests if a gentle electrical current applied to the head can help people with major depression. It's for adults currently in a depressive episode who haven't found relief from at least two previous antidepressants.
This trial tests a new type of brain stimulation called theta-burst stimulation to see if it helps treat depression. It is for people aged 18-50 who are currently experiencing a major depressive episode and are on a stable antidepressant regimen.
This study tests a new type of brain stimulation that uses gentle electrical fields to target the area of the brain linked to emotions. It may help reduce depression symptoms without the side effects of medications.
Hear when a new Major Depressive Disorder trial opens
We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.