IV DNase for ICU sepsis with organ stress
Part of Infections clinical trials.
This Phase 1 study tests whether an IV medicine called DNase I can safely help people with sepsis who are having worsening organ function. It’s designed to see if the treatment is tolerated and could improve outcomes for ICU patients with early sepsis.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You’re 18 years or older
- You were admitted to the ICU within the last 48 hours
- Your doctor believes you have an infection causing your illness
- You have new/worsening organ stress from sepsis (SOFA score at least 2 higher than your baseline)
- You’re expected to stay in the ICU for at least 72 hours
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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