Leuprolide treatment for severe polycystic liver growth
Treatments studied
Part of Genetic & congenital, Kidney & urinary, Women’s health & pregnancy clinical trials.
This Phase 2 study tests whether a monthly hormone medicine (leuprolide, a GnRH agonist given as an injection) can slow down ongoing, fast-growing polycystic livers. It is aimed at pre-menopausal women with very large livers that are still getting bigger on past and current scans.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are assigned female at birth and are 18 to 45 years old
- You have polycystic liver disease with more than 10 liver cysts
- Your liver is very large for your age and is still growing on scan results
- You have at least one past MRI or CT scan from 1 to 5 years ago
- You are able to use a “somatostatin-type” liver medicine now, or have a documented reason you can’t
- You can safely have MRI scans and complete study questionnaires, and you can give written consent
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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