Chemo alone versus chemo with radiation after endometrial cancer surgery
Treatments studied
Part of Cancer, Women’s health & pregnancy clinical trials.
This trial compares chemotherapy alone with chemotherapy plus radiation after surgery for endometrial cancer. It is specifically for tumors that have a p53 mutation, to see which treatment helps prevent the cancer from coming back or progressing.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are 18 years or older.
- Your endometrial cancer is stage I through stage IVA (and it was found/sorted with surgical staging, including lymph node mapping/biopsy such as sentinel lymph node biopsy).
- Your tumor testing shows a p53 mutation from a pre-surgery biopsy or surgery specimen.
- You started the planned post-surgery treatment within 8 weeks of enrollment.
- Your blood counts and organ function tests are adequate (enough white blood cells and platelets, and acceptable liver/kidney results).
- You can do the study treatments: you can receive chemotherapy and, if assigned, chemo plus radiation, and you agree to follow study rules.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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