Alverine test to lower high pressure in the liver
Part of Digestive system clinical trials.
This trial studies alverine to lower portal hypertension, which is high blood pressure in the liver that can happen with cirrhosis. If it works safely, it may reduce pressure-related complications in people with confirmed liver scarring.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are between 18 and 75 years old
- You have confirmed cirrhosis (diagnosed on scan or liver biopsy)
- Your portal pressure is at least 10 mmHg
- You agree to take part by signing informed consent
- You have not taken non-selective beta-blockers or statins in the past month
- You do not have recent serious complications (like bleeding, major confusion, or major belly fluid buildup) in the past week
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
Similar studies
Other trials that look related to this one.
This trial tests a new type of stent placed inside the liver to lower high blood pressure in the portal vein (a major vein that carries blood to the liver). It is aimed at people with cirrhosis who have serious complications like bleeding in the esophagus or stomach, or fluid buildup in the belly that does not go away. The study will see how safe and effective this stent is.
This trial is for people with liver cirrhosis who have high blood pressure in the vein that carries blood to the liver (portal hypertension). It uses a special ultrasound with contrast to learn more about the condition.
This study is checking if it is safe for people with cirrhosis (liver scarring) to stop taking a certain blood pressure medicine (non-selective beta blockers) if their main liver problem is under control. If you've had varices or bleeding in the past and your liver is now stable, this trial will see if you can safely stop the medicine.
This trial tests a special stent to treat high blood pressure in the liver caused by cirrhosis. It may help patients who need a procedure called TIPS to improve blood flow.
This study tests a medicine called carvedilol (a non-selective beta-blocker) to see if it can prevent complications in people with advanced chronic liver disease who are at high risk but haven't had serious problems like bleeding yet.
This trial looks at people with clinically significant portal hypertension, which is high blood pressure in the liver's blood vessels. It may help find better ways to manage this condition.
Hear when a new Portal Hypertension trial opens
We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.