Beta-blocker study for early-stage liver scarring
Treatments studied
Part of Digestive system clinical trials.
This study tests a medicine called carvedilol (a non-selective beta-blocker) to see if it can prevent complications in people with advanced chronic liver disease who are at high risk but haven't had serious problems like bleeding yet.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are 18 years or older.
- You have been diagnosed with chronic liver disease caused by alcohol, hepatitis B, hepatitis C, or fatty liver disease (MASLD).
- Your liver stiffness measurement and platelet count must show you are at high risk for developing serious liver problems, as defined by specific medical criteria.
- You must not have moderate-to-large esophageal varices (enlarged veins in the food pipe) or any other serious liver complications like cirrhosis with fluid buildup, bleeding, or brain issues.
- You are not currently taking a non-selective beta-blocker (like carvedilol or propranolol) and have not taken one in the last 6 months.
- You do not have conditions that make beta-blockers unsafe, such as slow heart rate, low blood pressure, asthma, or certain heart blocks.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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