Carvedilol for preventing liver complications in early cirrhosis
Part of Digestive system clinical trials.
This trial tests whether a long-term medicine called carvedilol can prevent liver failure or death in people with early-stage cirrhosis and high pressure in the liver's blood vessels. It may help delay serious complications and improve outcomes.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You must be at least 18 years old.
- You have cirrhosis caused by hepatitis B or C (with no active virus for 2+ years), or by alcohol, or by metabolic conditions (with a BMI under 30).
- A Fibroscan test within the last year showed a liver stiffness of 25 kPa or higher.
- You have no history of major complications like bleeding from varices, ascites, or encephalopathy in the past year.
- You have no serious heart conditions or severe lung disease that would make beta-blockers unsafe.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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