Clin2
NCT05523869Possibly a fitRecruiting

Eye injection medicine after repeat retinal detachment surgery

Proliferative Vitreoretinopathy in Rhegmatogenous Retinal Detachment

Part of Eyes & vision clinical trials.

This Phase 2 trial tests an injection of topotecan into the eye after surgery for retinal detachment that keeps coming back due to scar tissue (proliferative vitreoretinopathy). It may help improve how the retina heals after difficult, repeat operations when vision is usually very guarded.

Summary written for real people, not researchers, by Clin2.

Phase
Phase 2
Enrollment
50 people
Ages
18 years and older
Study type
Interventional

Who can take part

  • You are 18 years old or older.
  • You had repeat retinal detachment surgery (vitrectomy and/or scleral buckle) in the same eye because the detachment came back due to scar tissue (PVR).
  • Your retinal detachment is graded as PVR C or D (more severe scarring stages).
  • You have already had at least one retinal detachment surgery in that same eye before, and there is documentation that the retina detached again after that surgery.
  • You are able and willing to follow the study plan (go to visits, follow instructions).
  • If you plan to have cataract surgery at the same time as the detachment surgery, you may still be eligible.

View the official record on ClinicalTrials.gov

Quick eligibility check

Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.

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