Guidance method for opening heart blockages with stents
Part of Heart & circulation clinical trials.
This study compares two ways of deciding how completely to open blocked heart arteries using drug-eluting stents. It aims to see which guidance approach improves results and safety for people with coronary artery disease who need a PCI (heart catheter procedure).
Summary written for real people, not researchers, by Clin2.
Who can take part
- You’re age 19 or older and have coronary artery disease with chest pain or proof of reduced blood flow to the heart
- Your coronary artery blockages are in major vessels and are about 50% to 90% narrowed (and the vessel is at least 2.25 mm wide)
- You must be able to sign the consent form (or your guardian can) and agree to follow-up visits and study procedures
- You should not have coronary artery bypass surgery in the past
- You likely should not have pregnancy/breast-feeding, and you must be able to take required blood-thinning medicines (aspirin and another antiplatelet like clopidogrel/prasugrel/ticagrelor)
- You should not have certain situations that make testing or the procedure unsafe, like severe vessel twisting that prevents a pressure test, left heart pumping being too weak (ejection fraction under 35%), or a life expectancy under 1 year
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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