Clin2
NCT05530343Possibly a fitRecruiting

Two ways to sample tissue during Barrett’s follow-up

Barrett EsophagusBarretts Esophagus With DysplasiaEsophageal Adenocarcinoma

Part of Cancer, Digestive system clinical trials.

This study compares two tissue-collection methods during an endoscopy for Barrett’s esophagus to see which one detects concerning changes better. Your results could help improve how doctors check Barrett’s over time.

Summary written for real people, not researchers, by Clin2.

Phase
N/A
Enrollment
2,298 people
Ages
18 years to 89 years
Study type
Interventional

Who can take part

  • You are having an endoscopy to check Barrett’s esophagus (either routine follow-up or initial screening)
  • Your Barrett’s esophagus is at least a minimum length (at least M1)
  • You speak English or Spanish and can understand and sign the consent form
  • You are age 18 to 89 and expected to live at least 2 more years
  • You have no history of treatments to remove Barrett’s using “endoscopic eradication therapy” (EET)

View the official record on ClinicalTrials.gov

Quick eligibility check

Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.

Similar studies

Other trials that look related to this one.

NCT07212491Enrolling by invitation
New ways to detect early esophageal changes in Barrett's esophagus

This study tests a new, less invasive way to detect precancerous changes or early cancer in Barrett's esophagus. It uses a sponge or brush to collect cells from your esophagus during a routine endoscopy, which may help find problems earlier and avoid more invasive procedures.

Scottsdale, Arizona
NCT03961945Recruiting
Testing a new way to diagnose Barrett’s esophagus

This study tests minimally invasive, sample-based tests during an endoscopy to find Barrett’s esophagus and help sort it from esophageal cancer risk. It may help doctors spot changes earlier and more accurately using less invasive methods than standard tissue testing alone.

Scottsdale, Arizona
NCT07206589Not yet recruiting
New ways to screen for Barrett's esophagus

This trial tests two simple, non-surgical methods to look for Barrett's esophagus (a change in the lining of the swallowing tube) and early esophageal cancer. It is for people who are at higher risk or lower risk, but have never had Barrett's or cancer before.

Scottsdale, Arizona
NCT06071845Recruiting
Testing a simpler sponge test for Barrett's esophagus

This study tests a new, less invasive way to collect cells from the esophagus using a small sponge on a string (called Cytosponge). It aims to see if this method can accurately detect Barrett's esophagus, a condition that can raise the risk of esophageal cancer.

Scottsdale, Arizona
NCT05642338Recruiting
Testing two sampling methods to monitor Barrett’s esophagus

This study compares two ways of taking tissue samples during endoscopy to check how Barrett’s esophagus is changing. The goal is to improve surveillance, especially for finding early precancer or early cancer changes.

Amsterdam, North Holland
NCT04312633Recruiting
Testing a new throat biopsy mapping method for Barrett’s disease

This study follows people for 5 years to see how well a new biopsy-mapping test (WATS3D) works during routine upper endoscopy. It may help doctors find Barrett’s esophagus changes earlier and better guide follow-up after treatment.

Bethpage, New York

Hear when a new Barrett Esophagus trial opens

We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.