Testing a simpler sponge test for Barrett's esophagus
Part of Cancer, Digestive system clinical trials.
This study tests a new, less invasive way to collect cells from the esophagus using a small sponge on a string (called Cytosponge). It aims to see if this method can accurately detect Barrett's esophagus, a condition that can raise the risk of esophageal cancer.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are 18 to 90 years old.
- You have known or suspected Barrett's esophagus, or you are having a routine endoscopy for other reasons.
- You are not pregnant or breastfeeding.
- You are not taking blood thinners (unless you can stop them for 3–5 days before the procedure).
- You do not have trouble swallowing, a history of certain esophagus conditions, or a recent cancer in the upper digestive tract.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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This study tests less invasive ways to detect high-grade dysplasia (very abnormal cells) and esophageal cancer in people with Barrett's esophagus, a condition that can increase cancer risk. It looks for these changes using cell samples taken during a routine endoscopy, which may be quicker and more comfortable than standard biopsies.
This study tests a less invasive way to check for Barrett's esophagus and esophageal cancer. Instead of a standard endoscopy, they may use a sponge-on-a-string or other simpler methods, which could be more comfortable and easier for patients.
This study compares two tissue-collection methods during an endoscopy for Barrett’s esophagus to see which one detects concerning changes better. Your results could help improve how doctors check Barrett’s over time.
This trial tests a device that collects cells from the esophagus using a swallowed capsule, which may detect Barrett's esophagus without a standard endoscopy. It is for people who are already scheduled for an endoscopy.
This trial tests if a capsule-sponge device can replace endoscopy for monitoring people with ultralong-segment Barrett's esophagus. It aims to make surveillance easier and less invasive.
This study compares two ways of taking tissue samples during endoscopy to check how Barrett’s esophagus is changing. The goal is to improve surveillance, especially for finding early precancer or early cancer changes.
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