Testing two sampling methods to monitor Barrett’s esophagus
Part of Cancer, Digestive system clinical trials.
This study compares two ways of taking tissue samples during endoscopy to check how Barrett’s esophagus is changing. The goal is to improve surveillance, especially for finding early precancer or early cancer changes.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are at least 18 years old
- You have Barrett’s esophagus with a certain measured size (extent) on endoscopy reports
- You’re in one of these situations: new work-up for low-grade/high-grade dysplasia or early-stage low-risk cancer, or routine surveillance for known Barrett’s without dysplasia in the past 18 months
- You can read, understand, and sign consent forms and follow the study’s follow-up plans
- At the time of the planned sampling, there should be no visible suspicious spots on the esophagus (unless from prior treatment)
- You should not have had certain prior treatments or issues, like esophageal ablation, certain types of cancer-risk findings after resection, or esophageal varices
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
Similar studies
Other trials that look related to this one.
This study looks at how Barrett's esophagus affects your quality of life and fear of cancer. It uses new tests to better predict who might develop esophageal cancer, so you can get the right care sooner.
This trial tests a new risk model to predict if early Barrett's esophagus-related cancer may return. It also looks at how telling patients their risk affects their quality of life and fear of cancer. If you have Barrett's with a small, early cancer, this study may help decide the best follow-up plan for you.
This study compares two tissue-collection methods during an endoscopy for Barrett’s esophagus to see which one detects concerning changes better. Your results could help improve how doctors check Barrett’s over time.
This study follows people for 5 years to see how well a new biopsy-mapping test (WATS3D) works during routine upper endoscopy. It may help doctors find Barrett’s esophagus changes earlier and better guide follow-up after treatment.
This study tests minimally invasive, sample-based tests during an endoscopy to find Barrett’s esophagus and help sort it from esophageal cancer risk. It may help doctors spot changes earlier and more accurately using less invasive methods than standard tissue testing alone.
This trial tests two simple, non-surgical methods to look for Barrett's esophagus (a change in the lining of the swallowing tube) and early esophageal cancer. It is for people who are at higher risk or lower risk, but have never had Barrett's or cancer before.
Hear when a new Barrett Esophagus trial opens
We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.