UTD1 plus capecitabine for HER2-negative breast cancer brain mets
Part of Brain & nervous system, Cancer clinical trials.
This trial tests whether adding a study drug called UTD1 to capecitabine can shrink or control breast cancer that has spread to the brain. It’s for people with HER2-negative metastatic breast cancer who have brain metastases and meet specific safety and lab requirements.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are 18 to 70 years old
- Your breast cancer is HER2-negative (IHC or FISH test results confirm this)
- You have at least one brain metastasis spot seen on MRI that is big enough (at least 10 mm by the longest measurement)
- Your performance status is good (ECOG score 0 to 2, meaning you’re able to care for yourself and do light activities)
- Blood, liver, and kidney tests are within required safety ranges (including hemoglobin and white blood cell and neutrophil counts above set minimums)
- Your prior treatments fit the timing rules (no recent capecitabine in the last 6 months, and no recent major anti-cancer therapies that conflict with the study)
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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