Clin2
NCT05541822Possibly a fitRecruiting

Study drug for lung cancer with specific c-MET changes

Advanced Solid Tumors

Treatments studied

Part of Cancer clinical trials.

This Phase 2 study tests ABN401 to see how well it works and how safe it is for people with advanced non-small cell lung cancer (NSCLC) that has certain c-MET (a protein) changes. It may help some tumors that have not responded well to prior treatment, especially certain EGFR-related cases.

Summary written for real people, not researchers, by Clin2.

Phase
Phase 2
Enrollment
178 people
Ages
18 years and older
Study type
Interventional

Who can take part

  • You are age 18 or older (or the local adult age of majority).
  • Your health status is ECOG 0–1 (you can do most daily activities).
  • You have at least 1 measurable lung tumor spot on scans.
  • Your cancer must be NSCLC that has spread or returned, and it must match one of the trial’s c-MET/EGFR situation groups.
  • You can’t have had prior c-MET (MET) inhibitor medicines or HGF-targeting treatments.
  • You must be able to provide required tumor tissue and blood samples (fresh or stored tissue is often allowed).

View the official record on ClinicalTrials.gov

Quick eligibility check

Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.

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