Closing a leaky heart connection early in very small babies
Part of Genetic & congenital, Heart & circulation clinical trials.
This trial compares an early procedure to close a heart vessel called the ductus arteriosus versus careful observation alone in very low-birth-weight preterm infants. It aims to see whether closing the vessel early can improve outcomes and be done safely.
Summary written for real people, not researchers, by Clin2.
Who can take part
- Baby was born between 22 and 28 weeks of pregnancy
- Birth weight is at least 700 grams
- Baby is in a NICU study unit and is on a breathing machine when enrolled
- An ultrasound (echocardiogram) shows a leak pattern that meets a PDA score of 6 or higher
- Randomization happens within 5 days after the qualifying ultrasound, and the baby is 7 to 32 days old at enrollment
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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