Personalized treatment for preterm babies with open heart vessel
Part of Heart & circulation clinical trials.
This study tests a personalized approach to treating a common heart condition in very early preterm babies, where a blood vessel (the ductus arteriosus) stays open. It aims to find the best time and way to close this vessel using medication, based on the baby's specific biomarkers.
Summary written for real people, not researchers, by Clin2.
Who can take part
- The baby must be born before 32 weeks of pregnancy.
- The baby cannot have severe heart defects other than the open duct (PDA).
- The baby cannot have major birth defects, chromosomal problems, or severe brain issues.
- The baby cannot have severe infection, bleeding problems, or organ failure.
- The baby cannot have been treated for PDA with other medications before.
- The baby must not have contraindications to ibuprofen, like active stomach bleeding or kidney problems.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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