CBT therapy study for anxiety and brain circuit changes
Part of Blood & lymphatic, Cancer, Immune system & allergy, Mental health clinical trials.
This trial studies whether a specific form of talk therapy (CBT) changes brain activity in people with moderate anxiety. It may help your care team understand what works best and how brain “circuits” respond to treatment.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You’re currently enrolled in IAPT Step 3 (high-intensity anxiety support).
- Your GAD-7 anxiety score is 8 or higher, but not above 22.
- You can read, understand, and sign written consent.
- You can stop and avoid starting anxiety-related medicines if you take them now: no psychotropic meds currently, and none in the last 3 months.
- You can safely complete an MRI scan (no contraindications like certain implants/metal or severe claustrophobia).
- You’re not pregnant, planning pregnancy, or breastfeeding (for female participants).
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
Similar studies
Other trials that look related to this one.
This study tests whether a type of talking therapy that helps people cope with uncertainty is better than a relaxation technique. It might help reduce anxiety and worry.
This study looks at how people change during different types of psychotherapy for anxiety and depression. It aims to understand which treatments work best for different people.
This trial tests a neuro-based treatment to help adolescents with generalized anxiety disorder, including those newly diagnosed. You may be able to join if you meet age, diagnosis, and safety requirements, and if you have not already tried certain mindfulness programs.
This trial tests a psychotherapy approach to help veterans and service members who have PTSD and/or anxiety disorders. You may be randomly assigned to different therapy conditions, and the study aims to improve quality of life and reduce anxiety and PTSD symptoms.
This trial tests if a combination of non-invasive brain stimulation (tDCS) and virtual reality meditation can reduce anxiety in people with Generalized Anxiety Disorder or related conditions. It aims to find a new, non-medication way to help manage symptoms.
This trial is checking if a version of CBT-GSH (Cognitive Behavioral Therapy Guided Self-Help) works well for people who've had it before and are coming back for help with anxiety or depression. You'd get the same kind of low-intensity support again.
Hear when a new Anxiety Disorders trial opens
We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.