Clin2
NCT05557695Possibly a fitRecruiting

Acalabrutinib patient study for early access CLL in the UK

Chronic Lymphocytic Leukemia, CLL

Treatments studied

Part of Blood & lymphatic, Cancer, Immune system & allergy clinical trials.

This observational study follows adults in the UK who started acalabrutinib through an early access program for chronic lymphocytic leukemia (CLL). It aims to learn what happens in real-world care after starting the medicine.

Summary written for real people, not researchers, by Clin2.

Phase
N/A
Enrollment
350 people
Ages
18 years to 130 years
Study type
Observational

Who can take part

  • You have been diagnosed with CLL (or sometimes small lymphocytic lymphoma, SLL).
  • You did not take acalabrutinib before (you started it for the first time).
  • You started acalabrutinib through the UK Early Access Programme (not routine care).
  • Your first dose was between April 1, 2020 and April 1, 2021.
  • You are 18 years old or older.

View the official record on ClinicalTrials.gov

Quick eligibility check

Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.

Similar studies

Other trials that look related to this one.

NCT07024706Recruiting· Phase 2
Study of acalabrutinib plus venetoclax for relapsed CLL

This trial tests a combination of two targeted drugs for people with CLL or SLL whose cancer returned after first treatment with a similar type of therapy. The goal is to see if this approach works well with a fixed treatment duration.

Boston, Massachusetts
NCT07288515Recruiting
Acalabrutinib for CLL in routine care

This study follows people with CLL who are starting acalabrutinib (a targeted pill) for the first time, either as their first treatment or after previous therapies. The goal is to see how well it works in everyday medical practice.

Grodno
NCT06767891Enrolling by invitation
Real-world study of acalabrutinib for MCL or CLL

This study looks at how acalabrutinib works in real-world everyday medical practice for people with MCL or CLL who have already had at least one prior treatment. The goal is to see how well the drug performs outside of a strict research setting.

Shanghai, Shanghai Municipality
NCT03516617Recruiting· Phase 2
Acalabrutinib with or without obinutuzumab for early CLL/SLL

This Phase 2 trial studies whether acalabrutinib, and optionally adding obinutuzumab, can control early-stage chronic lymphocytic leukemia (CLL) or small lymphocytic lymphoma (SLL). It aims to see how well these treatments work and how safe they are in people who have not had prior treatment.

Scottsdale, Arizona
NCT06757647Recruiting· Phase 2
Acalabrutinib for CLL/SLL patients with heart issues from ibrutinib

This trial tests a different targeted drug, acalabrutinib, for people with CLL or SLL who developed heart problems (like atrial fibrillation) while taking ibrutinib. The goal is to see if acalabrutinib can control the cancer without causing the same heart side effects.

Columbus, Ohio
NCT06651970Recruiting· Phase 4
Acalabrutinib for chronic lymphocytic leukemia with heart problems

This trial tests a targeted therapy called acalabrutinib (a pill) against other standard treatments for chronic lymphocytic leukemia (CLL) in people who also have heart conditions. The goal is to see if acalabrutinib is a safer or more effective option for this group.

Charlotte, North Carolina

Hear when a new Chronic Lymphocytic Leukemia, CLL trial opens

We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.