Shingles vaccine safety study for people with lupus
Part of Immune system & allergy, Skin clinical trials.
This Phase 4 study checks how safe a shingles vaccine (Shingrix, a non-live vaccine) is for adults with lupus. You might be invited if you have lupus and haven’t had certain shingles or chickenpox-related vaccines recently, and if your lupus symptoms and immune health meet the study rules.
Summary written for real people, not researchers, by Clin2.
Who can take part
- Be an adult (18+) and able to give informed consent before any study steps
- Have lupus confirmed by the study’s SLE criteria (doctor-confirmed lupus diagnosis that fits 2019 EULAR/ACR rules)
- Use reliable birth control during the study (or meet an approved pregnancy-free situation such as being surgically sterile, 1+ year past menopause, or consistently not having sex)
- No prior shingles vaccine Shingrix (or live shingles vaccine Zostavax) and no shingles infection in the last 12 months
- No major lupus flare at screening (flare rules based on rSFI and SLE activity) and no worsening lupus signs right at enrollment
- Avoid certain recent vaccines and immune medicines (no vaccines within 6 weeks, and no rituximab or cyclophosphamide within 9 months)
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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