Clin2
NCT05579366Possibly a fitRecruiting

Study of rinatabart sesutecan for advanced solid tumors

High Grade Epithelial Ovarian CancerHigh Grade Serous Ovarian CancerPrimary Peritoneal CarcinomaFallopian Tube CancerEndometrial CancerNon-small Cell Lung CancerEpidermal Growth Factor Receptor (EGFR)-Mutated Non-Small Cell Lung Cancer (NSCLC)Mesothelioma

Treatments studied

Part of Cancer, Hormones & metabolism, Lungs & breathing, Skin, Women’s health & pregnancy clinical trials.

This trial tests an investigational drug called rinatabart sesutecan (also known as Rina-S) for people with advanced solid tumors, including ovarian, endometrial, lung, breast, and other cancers. The drug is designed to target and kill cancer cells, and the study aims to see if it is safe and effective.

Summary written for real people, not researchers, by Clin2.

Phase
Phase 1/Phase 2
Enrollment
952 people
Ages
18 years and older
Study type
Interventional

Who can take part

  • You have a type of cancer that has spread or cannot be removed by surgery, such as ovarian, endometrial, lung, breast, mesothelioma, or cervical cancer.
  • You have already tried standard treatments that are known to help your type of cancer.
  • Your cancer can be measured on scans (like CT or MRI).
  • You have not had a type of lung inflammation called interstitial lung disease that required steroids in the past 2 years, and you do not have it now.
  • You have not previously been treated with a type of drug called a topoisomerase 1 inhibitor antibody-drug conjugate (like trastuzumab deruxtecan).

View the official record on ClinicalTrials.gov

Quick eligibility check

Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.

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