Clin2
NCT05590455Possibly a fitRecruiting

Testing a TNF-blocking drug to reduce death in HIV and TB meningitis

Tuberculous MeningitisHIV I Infection

Treatments studied

Part of Brain & nervous system, Infections clinical trials.

This Phase 2 trial studies whether a TNF-blocking medicine can lower the risk of death in people with HIV who also have TB meningitis. You would receive standard TB meningitis treatment plus the study drug, if you meet the criteria.

Summary written for real people, not researchers, by Clin2.

Phase
Phase 2
Enrollment
130 people
Ages
18 years and older
Study type
Interventional

Who can take part

  • Be 18 years or older
  • Have HIV infection
  • Have definite or probable TB meningitis
  • Start standard TB meningitis treatment no more than 3 days ago (including anti-TB drugs at standard doses and high-dose dexamethasone)
  • Be able to give consent (you or a close relative) for study participation

View the official record on ClinicalTrials.gov

Quick eligibility check

Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.

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