NAC to prevent lung damage after TB treatment
Treatments studied
Part of Infections clinical trials.
This trial tests if taking N-acetylcysteine (NAC) alongside standard TB treatment can help prevent long-term lung problems after tuberculosis. It is for people with moderate to severe TB who already have some reduced lung function.
Summary written for real people, not researchers, by Clin2.
Who can take part
- Be between 18 and 65 years old
- Have confirmed drug-sensitive TB and moderate to severe lung changes on chest X-ray
- Have a lung function test (FEV1) at 65% or less of what is expected for your age, height, sex, and race
- Weigh between 30 and 90 kg (about 66 to 198 pounds)
- If you are a woman of childbearing age and sexually active, be willing to use birth control during the study
- If you have HIV, your CD4 count must be 100 or higher and you must be on or willing to start HIV treatment
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
Similar studies
Other trials that look related to this one.
This trial tests whether two natural supplements—silymarin (milk thistle) and n-acetylcysteine—can protect the liver from damage caused by tuberculosis medications. If you qualify, you will receive one of these supplements along with your TB treatment to see which one helps prevent liver problems.
This study looks at your lung health and overall wellbeing after finishing treatment for tuberculosis (TB). It aims to understand how TB affects breathing and quality of life, so doctors can better support recovery.
This trial tests a special exercise and breathing program for people who still have lung problems after being treated for tuberculosis. If you join, you may get this program, which could help you breathe easier and do more in your daily life.
This study tests whether two medicines, metformin and N-acetylcysteine, can help your lungs heal better after tuberculosis (TB). You will receive one of these study drugs along with your regular TB treatment.
This trial studies whether atorvastatin (a cholesterol medicine) can reduce ongoing inflammation after you finish standard tuberculosis (TB) treatment. If it works, it may improve how your body recovers after TB, especially by lowering inflammation-related signals.
This study tests different treatment plans for people with tuberculosis (TB) that can be cured with standard medicines. It aims to find the best treatment for each person based on their risk score, which may lead to shorter or more effective treatment.
Hear when a new Tuberculosis (TB) trial opens
We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.