NAC to prevent lung damage after TB treatment
Treatments studied
Part of Infections clinical trials.
This trial tests if taking N-acetylcysteine (NAC) alongside standard TB treatment can help prevent long-term lung problems after tuberculosis. It is for people with moderate to severe TB who already have some reduced lung function.
Summary written for real people, not researchers, by Clin2.
Who can take part
- Be between 18 and 65 years old
- Have confirmed drug-sensitive TB and moderate to severe lung changes on chest X-ray
- Have a lung function test (FEV1) at 65% or less of what is expected for your age, height, sex, and race
- Weigh between 30 and 90 kg (about 66 to 198 pounds)
- If you are a woman of childbearing age and sexually active, be willing to use birth control during the study
- If you have HIV, your CD4 count must be 100 or higher and you must be on or willing to start HIV treatment
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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