Clin2
NCT05608213Possibly a fitRecruiting

Lenvatinib plus radiation seeds vs lenvatinib alone for liver cancer

Hepatocellular Carcinoma Non-resectable

Treatments studied

Part of Cancer, Digestive system clinical trials.

This Phase 3 trial compares lenvatinib plus implanted radiation seeds versus lenvatinib alone in people with liver cancer that no longer responds to TACE. It aims to improve how long patients can control the cancer inside the liver.

Summary written for real people, not researchers, by Clin2.

Phase
Phase 3
Enrollment
187 people
Ages
18 years to 75 years
Study type
Interventional

Who can take part

  • You have confirmed liver cancer (HCC) based on biopsy/cytology or a clinician’s diagnosis
  • Your liver cancer is considered “TACE-refractory” (TACE is no longer working) and/or the cancer returned after surgery or ablation
  • Your scans show at least one measurable tumor in the liver you can treat with the study plan
  • Your liver function is good enough for treatment (Child-Pugh A or B)
  • You are well enough day-to-day (ECOG 0 or 1) and expected to live at least 3 months
  • Your cancer has not spread outside the liver, and there is no major vessel blockage like main portal vein involvement

View the official record on ClinicalTrials.gov

Quick eligibility check

Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.

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