Study of heart vessel dysfunction seen on heart imaging
Part of Heart & circulation, Pain clinical trials.
This study looks at coronary microvascular dysfunction (small blood vessel problems in the heart) using heart imaging. It may help researchers understand causes of chest tightness with activity and shortness of breath when the main heart arteries are not blocked.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You have chest discomfort with activity and/or shortness of breath with activity
- Your symptoms match specific questionnaires (Seattle Angina and Rose Dyspnea)
- Your heart scan or angiogram shows no major blockage (no artery narrowing >50%, and FFR >0.80 if measured)
- Your heart pumping strength is normal (left ventricle ejection fraction 50% or higher) and you don’t have cardiomyopathy
- You don’t have significant heart valve disease (moderate or severe) and your kidneys are strong enough (eGFR 30 or higher)
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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