Clinical trials
Angina clinical trials
Below are recruiting angina clinical trials, each written for real people, not researchers. We’re tracking 90 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT04674449Recruiting
Tests a targeted plan for people with chest pain from heart artery disease
This study aims to match people with angina (chest pain from heart artery problems) to the most helpful treatment plan based on their test results. It’s done around the time doctors are planning an invasive heart scan to look at the coronary arteries.
CorkAges 18 years+ - NCT04988685Recruiting
Heart artery balloon treatment registry study for adults
This study follows adults with blocked heart arteries who are treated using a special type of balloon (drug-coated balloon) during a procedure. It aims to track real-world outcomes to better understand how well this treatment works for people with new blockages or previously treated vessel narrowing.
Lucerne, Canton of LucerneAges 18 years+ - NCT06075602Recruiting
Complex and calcified coronary artery disease: a registry study
This study watches how people with complex or calcified heart artery disease are treated (with stents or bypass surgery) and how they do over time. It aims to learn which treatments work best for tough blockages.
Lucerne, Canton of LucerneAges 18 years+ - NCT06424834RecruitingPhase 2/Phase 3
Targeted medicines for chest pain without blocked arteries
This study tests if specific heart medicines (like beta-blockers or calcium channel blockers) can help people with chest pain that is not caused by blocked arteries. It aims to treat the tiny blood vessels or spasms that may be the real cause of your pain.
Palo Alto, CaliforniaAges 18 years+ - NCT07103317Recruiting
Understanding heart blood flow in chest pain without blockages
This study looks at people who have chest pain but don't have major blockages in their heart arteries. It aims to understand how the tiny blood vessels and artery spasms might be causing symptoms, using special heart tests.
Prague, Česká RepublikaAges 18 years+ - NCT05711849RecruitingPhase 2
Stem cell treatment for long-lasting chest pain not helped by meds
This Phase 2 trial tests whether stem cells placed into the heart artery can safely reduce symptoms in people with “refractory” angina (chest pain) despite maximum heart-healthy medication. You may qualify if your chest pain is limiting your activity and other heart procedures (stents/bypass) aren’t possible or are too risky.
London, EnglandAges 18 years+ - NCT06692751Recruiting
Eye scan for microvascular angina
This study tests if a non-invasive eye scan (OCT-A) can detect changes in tiny blood vessels in the retina of people with chest pain caused by problems with the heart's small arteries (microvascular angina). If it works, it could be a simpler way to diagnose this condition.
DijonAges 18 years+ - NCT07386418Recruiting
Angina thresholds study for patients needing stent treatment
This trial is testing a new way to measure blood flow in the heart during exercise to better understand angina. You may be eligible if you have at least two blocked heart arteries and are scheduled for stent placement.
BasildonAges 18 years+ - NCT05102019Recruiting
Device implant for severe angina using a coronary sinus reducer
This trial tests whether implanting a small device in the heart’s coronary sinus can reduce symptoms in people with long-lasting “refractory” angina despite taking the usual heart medicines. It may help improve how much activity you can do and reduce angina-related limitations.
Phoenix, ArizonaAges 18 years+ - NCT06503640Recruiting
Microvascular dysfunction in angina patients
This study tests if chest pain with clear arteries is caused by tiny heart vessel problems. It may help find better treatments for patients whose arteries look normal on angiograms.
Beijing, Beijing MunicipalityAges 18 years+ - NCT07392281RecruitingEarly Phase 1
Macitentan for chest pain from small heart vessel issues
This study tests a medicine called macitentan to see if it helps people with chest pain caused by problems in the tiny heart blood vessels (not from big blockages). If you have angina but no major artery blockages, this trial might explore a new treatment option.
Beijing, Beijing MunicipalityAges 18–75 - NCT06811831RecruitingEarly Phase 1
Mactientan for chest pain from small heart artery problems
This trial tests if mactientan, a blood vessel relaxer, can improve chest pain in people with coronary microvascular angina—where small heart arteries don't work right even though larger ones are clear. It aims to help those with ongoing angina symptoms.
Beijing, Beijing MunicipalityAges 18–75 - NCT06939374Recruiting
Freezing heart arteries to stabilize high-risk plaques
This study tests a special cooling balloon to freeze and stabilize dangerous plaques in heart arteries that are not the main cause of your current symptoms. It aims to prevent future heart attacks.
AalstAges 18 years+ - NCT07449325Recruiting
Heart sinus reducer for chest pain from small vessel disease
This trial tests a device placed in a heart vein (the coronary sinus) to improve blood flow and reduce chest pain in people with coronary microvascular dysfunction (small blood vessel disease). It aims to help those who still have symptoms despite taking heart medications.
New Haven, ConnecticutAges 18 years+ - NCT03781492Recruiting
Treatment study for stable angina symptoms
This study looks at managing and treating stable angina, a type of chest discomfort that happens predictably with activity or stress. It may help find better ways to control symptoms and improve daily life, but you must not have certain recent heart events to join.
Zabrze, Silesian VoivodeshipAges 18 years+ - NCT03789552RecruitingPhase 3
Testing T89 to prevent chest pain during stable angina
This Phase 3 trial tests whether T89 reduces angina (chest pain caused by heart-related reduced blood flow) in people with stable angina. You may help confirm the treatment’s benefit by completing symptom tracking and exercise heart tests over several weeks.
Naples, FloridaAges 18–90 - NCT04606459Recruiting
Device trial for hard-to-treat heart chest pain from small vessels
This trial tests whether a small pressure-reducing device placed in a heart vein (the coronary sinus) can reduce symptoms in people with ongoing chest pain from tiny blood vessel problems. It is for angina that has not improved despite standard heart medicines, and only if special heart tests show reversible reduced blood flow.
Mainz, Rhineland-PalatinateAges 18–85 - NCT04873687Recruiting
ECP treatment for stable angina while waiting for heart care
This trial studies whether ECP (a non-surgical treatment that improves blood flow to the heart) can reduce symptoms in people with stable angina who may need or are waiting for heart bypass surgery, or are being managed with medicines instead. It may help you feel better and need less urgent care—if you meet the study’s medical and personal requirements.
Bandung, West JavaAges 18 years+ - NCT05230446Recruiting
Testing full stent treatment for heart artery blockages
This study looks at how well doctors can treat multiple blocked heart arteries using a specific drug-eluting stent, aiming to fully open them. It may help patients whose blockage pattern fits the study, but it does not include certain high-risk or special cases.
Rotterdam, South HollandAges 18–85 - NCT05786417RecruitingPhase 4
Medication comparison for older adults with stable heart pain
This trial tests which heart medications work best for older adults who have stable angina (predictable chest pain) and multiple other long-term health problems. You may be asked to start or adjust medications and attend regular follow-up visits to see which approach controls symptoms and outcomes.
New Haven, ConnecticutAges 65 years+ - NCT06092736RecruitingPhase 4
Danshen pill for chest pain with normal arteries
This trial tests if a traditional Chinese medicine pill (compound Danshen dripping pill) can help people who have chest pain on exertion but whose heart arteries appear normal or nearly normal on scans. If you have this type of chest pain and fit the criteria, you may be able to join.
Jinan, ShandongAges 30–75 - NCT06311461Recruiting
Acupuncture for stable chest pain
This trial tests whether acupuncture can help relieve symptoms of stable angina, a type of chest pain that happens when your heart isn't getting enough blood. If you have chest pain at least once a week and are already on heart medications, you may be able to join.
Los Angeles, CaliforniaAges 21 years+ - NCT06384846Recruiting
AI predicts heart attacks using white blood cells
This study tests whether an artificial intelligence tool can accurately predict a heart attack (acute coronary syndrome) by looking at the properties of your white blood cells. If successful, it could help doctors diagnose heart attacks faster from a simple blood sample.
Graz, Styria / SteiermarkAges 18 years+ - NCT06400290Recruiting
Balloon test to find which artery causes chest pain
This study tests a new way to find which blocked heart arteries are causing your chest pain. During a stent procedure, doctors will briefly block each artery to see which one triggers your symptoms. This might help them decide which blockages to treat.
BasildonAges 18 years+
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Common questions
- Are there clinical trials for angina?
- Yes. Clin2 currently lists 90 recruiting angina studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a angina trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a angina trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.