Clin2
NCT05635851Possibly a fitNot yet recruiting

Nitric oxide donors to prevent blood pressure spikes during bowel care after spinal cord injury

Spinal Cord InjuriesAutonomic Dysreflexia

Part of Brain & nervous system, Injuries & trauma clinical trials.

This study tests whether a medication that releases nitric oxide can prevent dangerous blood pressure increases (autonomic dysreflexia) that can happen during bowel care for people with spinal cord injury. It may help make bowel routines safer and more comfortable.

Summary written for real people, not researchers, by Clin2.

Phase
Phase 2
Enrollment
26 people
Ages
19 years to 80 years
Study type
Interventional

Who can take part

  • Had a traumatic spinal cord injury at least one year ago
  • Have a regular bowel care routine
  • Can communicate in English
  • Are 19 years old or older
  • Do not have a colostomy or use a ventilator
  • Do not have certain conditions or take certain medications (like erectile dysfunction drugs or nitroglycerin)

View the official record on ClinicalTrials.gov

Quick eligibility check

Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.

Similar studies

Other trials that look related to this one.

NCT06596291Recruiting· Phase 1/Phase 2
Study of an injected treatment for bladder control after spinal cord injury

This trial tests a new medication injected directly into the bladder muscle to help reduce urine leakage in people with spinal cord injuries. It is for those who have tried other treatments without enough success and are considering more invasive options.

Downey, California
NCT07504055Recruiting
Non-invasive spinal cord stimulation for blood pressure after injury

This study tests whether a non-invasive spinal cord stimulation device can help regulate blood pressure in people with spinal cord injury who have low blood pressure symptoms. It may help you feel less dizzy or faint when you sit or stand up.

Louisville, Kentucky
NCT05731986Recruiting
Skin nerve stimulation to raise blood pressure after spinal injury

This study tests whether a device that delivers mild electrical stimulation through the skin can improve low blood pressure after an acute spinal cord injury. It may help reduce episodes of dizziness or faint-feeling caused by blood pressure dropping when you sit up.

West Orange, New Jersey
NCT06000592Recruiting
Spinal stimulation to stabilize blood pressure after spinal cord injury

This trial tests whether a non-invasive device that sends gentle electrical pulses to the spinal cord can help people with a recent spinal cord injury keep their blood pressure steady. It's designed for those who experience low blood pressure when sitting or standing, which can cause dizziness or fainting.

New York, New York
NCT05616910Enrolling by invitation· Phase 2
Inhaled nitric oxide for microvascular problems after brain injury

This Phase 2 study tests whether inhaled nitric oxide can improve tiny blood-flow problems in the brain after traumatic brain injury. If you qualify, you may receive inhaled nitric oxide and be monitored for safety and recovery.

Philadelphia, Pennsylvania
NCT02897063Recruiting· Phase 1
Test medicines for low blood pressure in nerve-related disorders

This early (Phase 1) study tests whether midodrine and droxidopa can improve blood-flow pooling in the belly in people with nerve problems that affect blood pressure when standing. It’s looking at safety and how the body responds, which may help reduce dizziness or fainting for some participants.

Nashville, Tennessee

Hear when a new Spinal Cord Injuries trial opens

We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.