Sentinel lymph node mapping to reduce leg swelling after surgery
Treatments studied
Part of Cancer clinical trials.
This study tests whether a special way of finding lymph nodes during hysterectomy can lower the risk of long-term leg swelling or related dysfunction in people with stage I endometrial cancer. It compares standard lymph node assessment with sentinel lymph node mapping and looks at how this affects day-to-day leg functioning.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You’ve been diagnosed with endometrial cancer by biopsy and you’re planning a laparoscopic or robotic hysterectomy with lymph node assessment (biopsy within 90 days).
- Your cancer is stage I, and a recent checkup suggests it hasn’t spread to other areas.
- You’re age 18 or older and can take part with an activity level rated as 0–2 (able to do self-care and most daily activities).
- Your surgeon believes you can safely do pelvic lymph node removal (pelvic lymphadenectomy).
- You have no recent history of leg swelling/lymphedema, frequent leg infection (cellulitis), or a recent deep blood clot in the leg (within 90 days).
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
Similar studies
Other trials that look related to this one.
This study compares two ways to check lymph nodes during surgery for early-stage endometrial (uterine) cancer: sentinel node biopsy versus removing more lymph nodes. It may help find whether the less extensive approach can stage the cancer accurately with fewer side effects.
This trial tests whether a less invasive way to check if cancer has spread to lymph nodes (sentinel node biopsy) works as well as the standard method. It is for people with early-stage endometrial cancer having surgery.
This trial compares two ways to remove lymph nodes during hysterectomy for endometrial cancer that hasn't spread. The goal is to find which method works better with similar or fewer side effects.
This study compares two ways of removing lymph nodes during surgery for a high-risk type of uterine (endometrial) cancer with a p53 gene mutation. You would be randomly assigned to either removing only the sentinel (first few) lymph nodes or removing many lymph nodes, to see if the less invasive approach is just as good.
This study looks at women with low-risk endometrial cancer who had tiny amounts of cancer cells found in their sentinel lymph nodes during surgery. Doctors want to see if it's safe to avoid additional treatments like chemotherapy or radiation.
This trial compares two ways of removing lymph nodes during a vaginal minimally invasive surgery for early-stage endometrial cancer. It aims to find which method is safer and more effective.
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