Device test to lower blood DNA and NETs in sepsis
Part of Infections, Lungs & breathing clinical trials.
This trial tests a medical device (NucleoCapture) that may remove substances called circulating DNA and NETs from the blood in people with sepsis and breathing failure. The goal is to check safety and see whether it can improve blood markers and possibly outcomes.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are age 18 to 75
- You have proven or suspected lung-related sepsis and are on a breathing machine
- You have been on invasive mechanical ventilation for 48 hours or less
- Your lung oxygen test is very low (PaO2/FiO2 ≤ 200 mmHg, or ≤ 26.6 kPa)
- Your organ stress score (SOFA) is between 4 and 14
- A doctor (or legal decision-maker) can give consent for the study
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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