Skin biopsy study of stem-cell therapy for congenital heart disease
Part of Genetic & congenital, Heart & circulation clinical trials.
This early study takes a small skin sample to make a personalized type of heart stem cells in the future. It is testing whether this approach is safe and feasible for people with complex single-chamber congenital heart disease and advanced heart failure.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are age 18 to 40 and can understand and sign consent
- You have univentricular (single-chamber) congenital heart disease
- You have advanced heart failure with high symptom burden (NYHA class IV) and weak pumping (ejection fraction under 40%)
- Your heart doctors expect you may survive about 1 to 1.5 years when the skin sample is taken
- You are either waiting long for a transplant, were denied a transplant, or need a heart machine for support
- You can follow study visits and have someone able to help you—especially the first 3 weeks after treatment is given
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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