Stem cell injection for advanced heart failure
Part of Heart & circulation clinical trials.
This trial tests a treatment made from stem cells that are turned into heart muscle cells and injected directly into the heart. It is for people with advanced heart failure who are already on the best available medicines and who are scheduled to have bypass surgery.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are between 18 and 75 years old.
- You have advanced heart failure (NYHA class III or IV) caused by blocked arteries, even on the best medications.
- Your heart's pumping ability is 35% or less, measured by a heart MRI.
- You are already scheduled to have coronary artery bypass surgery (CABG).
- You can walk for 6 minutes and do not have conditions like active cancer, serious infections, or liver/kidney problems that would prevent the procedure.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
Similar studies
Other trials that look related to this one.
This trial tests a new treatment using heart muscle cells made from stem cells (iPSC-CMs) combined with either a heart pump (LVAD) or bypass surgery (CABG) for people with end-stage heart failure. The goal is to see if adding these cells can help the heart work better.
This early-phase study tests a lab-made heart tissue (“engineered myocardium”) placed surgically to help the heart work better in people with advanced heart failure. It mainly checks safety first, and also looks for signs the patch can improve heart function in selected patients.
This trial tests whether heart muscle cells made from stem cells, injected into the heart, can improve heart function in people with heart failure and a weak heart pump. It may be an option for those who are not getting enough help from other treatments.
This trial tests whether injecting special cells (cell therapy) can help the heart recover in people with advanced heart failure who are getting a mechanical heart pump (LVAD). It may offer a new way to improve heart function and quality of life.
This trial tests whether a special collagen patch containing stem cells can help people recover heart function after a heart attack. You would get the patch placed on your heart during bypass surgery.
This trial tests whether injecting special cells (HiCM-188) during bypass surgery can help improve heart function in people with advanced heart failure. The cells may help repair damaged heart tissue and improve your heart's ability to pump blood.
Hear when a new Heart failure trial opens
We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.