Stem cell injection for advanced heart failure
Part of Heart & circulation clinical trials.
This trial tests a treatment made from stem cells that are turned into heart muscle cells and injected directly into the heart. It is for people with advanced heart failure who are already on the best available medicines and who are scheduled to have bypass surgery.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are between 18 and 75 years old.
- You have advanced heart failure (NYHA class III or IV) caused by blocked arteries, even on the best medications.
- Your heart's pumping ability is 35% or less, measured by a heart MRI.
- You are already scheduled to have coronary artery bypass surgery (CABG).
- You can walk for 6 minutes and do not have conditions like active cancer, serious infections, or liver/kidney problems that would prevent the procedure.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
Similar studies
Other trials that look related to this one.
This trial tests whether injecting special heart muscle cells (made from stem cells) during a heart bypass or a heart pump surgery can help improve your heart's function. It is for people with severe heart failure who are already planning one of these surgeries.
This early-phase study tests a lab-made heart tissue (“engineered myocardium”) placed surgically to help the heart work better in people with advanced heart failure. It mainly checks safety first, and also looks for signs the patch can improve heart function in selected patients.
This trial tests whether injecting lab-grown heart cells into the heart can help people with heart failure whose heart pumps less than 40% of normal. It may help improve heart function and reduce symptoms.
This trial tests whether injecting special cells (cell therapy) can help the heart recover in people with advanced heart failure who are getting a mechanical heart pump (LVAD). It may offer a new way to improve heart function and quality of life.
This trial tests whether placing a special membrane with stem cells on the heart during bypass surgery can help improve heart function in people with a weak heart after a previous heart attack.
This study tests whether injecting special heart cells (called HiCM-188) into the heart during bypass surgery can help improve heart function in people with advanced heart failure. The goal is to see if the cells can strengthen the heart muscle and help you feel better.
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