Stem cell therapy during heart bypass surgery for weakened heart muscle
Part of Heart & circulation clinical trials.
This study tests a new treatment using donor stem cells injected into the heart during scheduled bypass surgery. The goal is to see if these cells help improve heart function in people with heart failure due to blocked arteries and a weak heart pump.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are scheduled to have heart bypass surgery (CABG).
- Your age is between 19 and 85.
- You have a diagnosis of heart failure caused by reduced blood flow to the heart (ischemic cardiomyopathy).
- Your heart's pumping ability (left ventricular ejection fraction) is 40% or less.
- You have symptoms of heart failure (shortness of breath, fatigue) that limit some activity (NYHA class II to IV).
- You are not planning any other major heart surgery (like valve repair) at the same time as the bypass.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
Similar studies
Other trials that look related to this one.
This trial tests whether injecting stem cells from umbilical cord tissue into the heart muscle during bypass surgery can improve heart function in people with chronic heart failure. It is for patients who are already scheduled for bypass surgery and have a weakened heart pump (LVEF between 21% and 40%).
This trial tests a treatment made from stem cells that are turned into heart muscle cells and injected directly into the heart. It is for people with advanced heart failure who are already on the best available medicines and who are scheduled to have bypass surgery.
This trial tests whether placing a special membrane with stem cells on the heart during bypass surgery can help improve heart function in people with a weak heart after a previous heart attack.
This study tests whether injecting special heart cells (called HiCM-188) into the heart during bypass surgery can help improve heart function in people with advanced heart failure. The goal is to see if the cells can strengthen the heart muscle and help you feel better.
This Phase 1 study tests a treatment made from stem cells to grow heart muscle cells (“cardiomyocytes”) for people with long-lasting (chronic) heart weakness after a prior heart attack. It aims to see if the therapy can improve heart function and is safe in carefully selected patients.
This trial tests whether injecting special heart muscle cells (made from stem cells) during a heart bypass or a heart pump surgery can help improve your heart's function. It is for people with severe heart failure who are already planning one of these surgeries.
Hear when a new Ischemic Cardiomyopathy trial opens
We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.