Ondansetron to prevent fainting during sleep
Treatments studied
Part of Heart & circulation clinical trials.
This trial tests whether the drug ondansetron can prevent fainting that happens during sleep or when waking up. It may help reduce how often you faint and improve your safety at night.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You have had at least one episode of fainting while asleep or waking up in the past year.
- A doctor has confirmed your fainting is syncope (a temporary drop in blood flow to the brain).
- Your heart is structurally normal (no major heart disease).
- You are at least 18 years old.
- You are not pregnant and are willing to use reliable birth control if needed.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
Similar studies
Other trials that look related to this one.
This Phase 2 study tests whether ondansetron can help prevent future fainting (vasovagal syncope) in adults who have had recent episodes. If it works, it may reduce how often you faint and improve safety in everyday situations.
This Phase 3 study tests whether atomoxetine can reduce how often vasovagal fainting happens. It may help people who have frequent fainting episodes with triggers like stress or standing for long periods.
This study looks at people who have had repeated fainting spells and still don’t know the cause. It tests whether different types of heart monitoring (like tilt testing or an ECG/heart tracing) can better explain what’s triggering syncope and guide prevention.
This trial helps emergency departments use a simple risk score to guide care for adults who faint. It looks at whether using these recommended steps improves how syncope (fainting) is assessed and managed in the ER.
This study tests a new way to detect and warn about fainting in people with certain types of syncope (temporary loss of consciousness). It may help those who have already had a specific fainting evaluation called an ARS assessment.
This trial tests whether ondansetron can help people with atrial fibrillation (an abnormal heart rhythm) around the time of elective catheter ablation. It may improve the safety or effectiveness of the procedure by targeting a pathway involved in heart rhythm events.
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