Long-term follow-up for inclisiran in young people with inherited high cholesterol
Treatments studied
Part of Genetic & congenital, Hormones & metabolism clinical trials.
This study follows people with HeFH or HoFH (inherited high cholesterol) who previously took inclisiran in specific pediatric ORION studies. It mainly checks long-term safety and how well the treatment continues to be tolerated over time.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You have been diagnosed with HeFH or HoFH (inherited high cholesterol)
- You already finished one of the pediatric ORION studies: ORION-16, ORION-13, ORION-20, or ORION-19
- Your study doctor feels you benefited from inclisiran during the earlier ORION study
- You did not “screen fail” and did not permanently stop the earlier study
- You did not have serious safety or tolerability problems linked to inclisiran in the earlier study
- You do not have any serious or uncontrolled medical issue that would interfere with the study or increase risk
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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