Treatment
Inclisiran clinical trials
We’re tracking 19 recruiting studies that include Inclisiran, each written for real people, not researchers, below.
Recruiting studies
- NCT07626281RecruitingPhase 1
Safety study of new inclisiran formulation for cholesterol
This trial tests a new version of inclisiran, a cholesterol-lowering medicine, to see if it is safe and works well. The study compares it to the current version. You may qualify if you have moderately high cholesterol but have never taken cholesterol medications.
Lenexa, KansasAges 18–60 - NCT06909565RecruitingPhase 4
Inclisiran to prevent heart and leg events after artery procedure
This study tests whether a twice-yearly injection called inclisiran can prevent heart attacks, strokes, or leg complications in people who recently had a procedure to open a blocked artery. You may be eligible if you had a heart or leg artery procedure within the last two weeks.
Alexander City, AlabamaAges 18 years+ - NCT07610278RecruitingPhase 2
Blood Pressure and Cholesterol Treatment Study
This study tests a combination of two new medications (QCZ484 and inclisiran) designed to lower both blood pressure and cholesterol levels. You may be a good fit if you have high blood pressure and high cholesterol that isn't fully controlled by current treatments.
Foley, AlabamaAges 18–75 - NCT06865885RecruitingPhase 4
Lowering cholesterol with inclisiran in people on many medications
This study tests a new injectable medicine called inclisiran for people who are already on many medications and have high cholesterol. It is designed for those who cannot lower their cholesterol enough with statins, especially if they have diabetes or other heart risks.
La Jolla, CaliforniaAges 18–85 - NCT07102628RecruitingPhase 3
Early treatment with inclisiran for heart attack patients
This study tests if starting inclisiran soon after a heart attack helps lower cholesterol further in patients already on statins. The goal is to see if early treatment can reduce future heart risks.
Capital Federal, Buenos AiresAges 18 years+ - NCT06597006RecruitingPhase 3
Study of inclisiran for children with homozygous familial high cholesterol
This trial tests a new medicine called inclisiran to lower very high cholesterol in children aged 2 to 12 who have a specific genetic condition (homozygous familial hypercholesterolemia, or HoFH). You may not need to change your current cholesterol treatments, and the study will check if inclisiran can help reduce your LDL cholesterol further.
San Francisco, CaliforniaAges 2–11 - NCT05682378RecruitingPhase 3
Long-term follow-up for inclisiran in young people with inherited high cholesterol
This study follows people with HeFH or HoFH (inherited high cholesterol) who previously took inclisiran in specific pediatric ORION studies. It mainly checks long-term safety and how well the treatment continues to be tolerated over time.
Boca Raton, FloridaAges 12–100 - NCT06287177Recruiting
Study on Inclisiran adherence and effectiveness
This study looks at how well people stick with and respond to the cholesterol-lowering drug Inclisiran. It aims to understand if the medicine works well over time in Italian patients.
NaplesAges 18 years+ - NCT06338293RecruitingPhase 4
Inclisiran plus statins for fragile heart plaque
This trial tests if adding inclisiran to your current statin can reduce dangerous, rupture-prone plaque in your heart arteries. It may help if you have a moderate blockage with thin-cap plaque and your LDL cholesterol stays high despite statins.
Nanjing, JiangsuAges 18–80 - NCT06597019RecruitingPhase 3
Study of inclisiran for children with high cholesterol
This trial tests a medicine called inclisiran to lower high cholesterol in children ages 6 to 12 with a genetic condition called heterozygous familial hypercholesterolemia (HeFH). It may help children who still have high cholesterol despite taking other treatments.
San Francisco, CaliforniaAges 6–11 - NCT06813911RecruitingPhase 3
Testing pelacarsen for high Lp(a) in heart disease patients
This trial tests a new medicine called pelacarsen for people with very high Lp(a) (a type of cholesterol) and existing heart or blood vessel disease. It aims to see if adding pelacarsen to your current cholesterol treatment can lower your Lp(a) levels further.
Birmingham, AlabamaAges 18–80 - NCT07581808RecruitingPhase 4
Two cholesterol drugs for heart disease prevention
This study tests two newer cholesterol-lowering medications (inclisiran and alirocumab) together in people who've had heart problems or strokes and cannot tolerate standard cholesterol drugs. The goal is to see if this combination safely lowers cholesterol further and reduces future cardiovascular events.
LjubljanaAges 18 years+ - NCT07142265Recruiting
Early inclisiran after heart attack trial
This trial tests if giving inclisiran early after a heart attack can lower cholesterol more effectively. It is for people who have had a recent heart attack and still have high LDL cholesterol despite taking statins.
CheboksaryAges 18–100 - NCT07704918Recruiting
Study: Lowering cholesterol during melanoma immunotherapy
This study tests whether giving aggressive cholesterol-lowering medication to people starting immunotherapy for melanoma can improve heart health. It may help reduce the risk of heart problems during cancer treatment.
Aurora, ColoradoAges 55 years+ - NCT06770543Recruiting
Study of Leqvio for high cholesterol in Korea
This study is for adults in Korea with high cholesterol who need a new option because statins aren't working well enough or cause side effects. It will look at how well the medication Leqvio works in everyday medical practice.
Yangsan, Gyeongsangnam-doAges 18–100 - NCT07543731Recruiting
Study of how patients stick with cholesterol-lowering injection medications
This study follows people who are starting one of three injectable cholesterol medications (inclisiran, evolocumab, or alirocumab) to see how well they stick with treatment over time. Understanding medication adherence helps doctors and patients find ways to improve long-term health outcomes.
BaselAges 18–99 - NCT04073797Recruiting
PET scan study of inflammation and cholesterol-lowering treatment
This study uses PET/CT and related scans to measure inflammation in artery plaque and how cholesterol-lowering treatment changes it. It may help researchers understand which treatments reduce artery inflammation for people with heart or blood-vessel disease and high LDL (“bad”) cholesterol.
CambridgeAges 18–99 - NCT06494501RecruitingPhase 3
Preventing heart attacks in middle-aged adults with early plaque
This study tests whether starting cholesterol-lowering treatment early can prevent heart attacks in people aged 30-50 who already have early signs of artery plaque but no history of heart disease.
New York, New YorkAges 30–50 - NCT06858332Recruiting
Lp(a) cholesterol in adults with heart and blood vessel disease in Russia
This study looks at levels of a type of cholesterol called Lp(a) in people with certain heart and blood vessel diseases. The goal is to understand how common high Lp(a) is in Russian adults with these conditions.
ChelyabinskAges 18–99
What Inclisiran is being studied for
Conditions with recruiting Inclisiran studies.
Common questions
- Are there clinical trials studying Inclisiran?
- Yes. Clin2 currently lists 19 recruiting studies that include Inclisiran, drawn from the U.S. registry and rewritten for real people so you can see what each is testing and who it's for.
- How do I know if I qualify for a Inclisiran trial?
- Each study lists its own eligibility criteria — rules about condition, age, and prior treatments. On every Clin2 trial page we explain these in plain language and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Is Inclisiran an approved treatment?
- A drug being studied in a trial may be investigational (still being tested) or already approved and being studied for a new use. Each study page explains what phase it's in. Clin2 does not provide medical advice — talk with your doctor about whether Inclisiran or a specific trial is right for you.
Related treatments
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. A drug appearing here is being studied in a trial and may be investigational. Talk with your doctor about whether a specific treatment or trial is right for you.