Testing prasugrel alone after stent placement for heart attack
Part of Heart & circulation clinical trials.
This study checks whether taking prasugrel by itself, after you get a drug-eluting stent for a heart attack (STEMI), can work as well as the standard approach. It may help prevent blood clots in the stent, but it requires specific blood-thinner plans for 12 months.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are having a planned emergency heart procedure (primary PCI) and will receive an everolimus drug-eluting stent (SYNERGY stent).
- Your diagnosis is a STEMI heart attack.
- You can safely take two blood-thinning medicines for 12 months (aspirin plus another medicine like a P2Y12 inhibitor).
- You are not taking any anticoagulant (a blood thinner such as warfarin or apixaban/rivaroxaban).
- You are 18 years or older and you are expected to live at least 1 year.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
Similar studies
Other trials that look related to this one.
This trial tests if a lower dose of prasugrel, taken alone (without aspirin), is safe and works well for people who have had a stent placed for chest pain or a heart attack. It might be an option for those who need to simplify their medication routine.
This trial compares two ways of using anti-platelet (blood-thinner) medicines after a specific kind of heart attack (STEMI) treated with a stent. It aims to see if switching sooner to one medicine (instead of two for longer) works just as well and may reduce risks.
This trial studies whether a specific stent (with no polymer coating) plus a single blood thinner plan with aspirin and another P2Y12 medicine is as safe and effective as the standard two-medicine plan after a STEMI heart attack. It may help people avoid longer exposure to stronger blood-thinning if the new approach works as well.
This study tests whether taking a single blood-thinning medication (instead of two) after heart stent placement is safe and effective over the long term. If you've recovered well from a stent procedure, this trial may help determine the safest way to prevent future heart problems.
This trial compares taking a shorter course of prasugrel (a blood thinner) plus aspirin after a heart attack versus the standard 12-month course. It aims to see if a shorter duration is just as effective and safer for people who got a specific type of stent (everolimus-eluting).
This trial tests if people who have been on two blood thinners (aspirin plus prasugrel or ticagrelor) for at least 90 days after getting a heart stent can safely switch to just one of those blood thinners. It aims to see if taking only one pill is as safe and effective as taking two.
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