Platelet-directed whole blood transfusion for malaria in young children
Part of Blood & lymphatic, Infections clinical trials.
This study is testing a new way to use whole blood transfusions to treat severe malaria in young children. It might help children with very low platelet counts and low hemoglobin recover better.
Summary written for real people, not researchers, by Clin2.
Who can take part
- Your child must be younger than 5 years old.
- Your child must have severe malaria (confirmed by a doctor) with a certain amount of the malaria parasite in their blood (at least 500 per microliter).
- Your child's platelet count must be low (100,000 or below) — platelets are small cells that help blood clot.
- Your child's hemoglobin must be between 5 and 11 g/dL — hemoglobin is the part of red blood cells that carries oxygen.
- You must live in the area served by the study clinic and be willing to follow the study plan.
- You must be able to give informed consent (permission) for your child to take part.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
Similar studies
Other trials that look related to this one.
This study tests a malaria treatment called PDMC in children under 10 who are in the hospital with severe anemia or severe malaria. It aims to see if this treatment can help prevent further health problems.
This trial tests whether giving malaria prevention medicine after hospital discharge helps prevent another serious malaria episode in young children. If your child was hospitalized for severe anemia or severe malaria, this study may offer additional protection.
This study looks at severe malaria in children from remote areas. It compares children with malaria, children with other severe fevers, and those with uncomplicated malaria to improve treatment in hard-to-reach villages.
This study looks at the best way to decide when to give platelet transfusions to very premature babies. It aims to help prevent bleeding while avoiding unnecessary transfusions.
This study compares two different amounts of platelet transfusions to see which is safer and more effective for premature babies with very low platelet counts. Platelets are tiny cells in the blood that help stop bleeding, so this treatment may reduce the risk of serious bleeding in the brain.
This study tests a new malaria treatment for children with mild (uncomplicated) malaria. The goal is to see if the treatment safely and effectively clears the infection.
Hear when a new Severe Malaria trial opens
We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.