Carotid implants to help prevent stroke repeat in atrial fibrillation
Part of Brain & nervous system, Heart & circulation clinical trials.
This trial tests whether placing a carotid implant can reduce the chance of having another stroke in people with atrial fibrillation who are already taking blood thinners. It aims to prevent stroke recurrence while you continue prescribed anticoagulation.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You have a documented history of atrial fibrillation (AF).
- You had a non-bleeding stroke (ischemic stroke) within a certain time window around enrollment, and brain scans showed stroke that improved within 24 hours.
- You plan to stay on a blood thinner for the whole study (either a vitamin K antagonist like warfarin or a DOAC).
- Your care team believes you can take one additional antiplatelet medicine (like aspirin or similar) along with your blood thinner for 6 months.
- Your neck artery anatomy must fit implant safety requirements on ultrasound or angiogram, with no major blockage (no 50% or more internal carotid narrowing) and no prior stent/dissection in the common carotid artery.
- You can sign informed consent.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
Similar studies
Other trials that look related to this one.
This study looks at the link between the type of atrial fibrillation (an irregular heartbeat that comes and goes) and the risk of having another stroke. It involves people who have had a recent ischemic stroke and have a certain type of AF.
This trial looks at ways to help people with atrial fibrillation lower their risk of stroke, premature death, and worsening memory. It may help by identifying which prevention approach works best for a broader community of patients.
This trial tests whether taking a blood thinner can lower the risk of stroke in people who had atrial fibrillation (an irregular heartbeat) that happened temporarily around a stressful illness or surgery. It looks especially at people at higher risk for stroke after that episode.
This trial tests whether starting blood thinners soon after a procedure to remove a blood clot from the brain can safely prevent another stroke in people who have atrial fibrillation. Participation is for those who had a severe stroke, received the clot-removal procedure, and are medically stable afterward.
This trial tests whether using a balloon guide catheter during carotid artery stenting helps prevent strokes during the procedure. It is for people who have significant narrowing in the carotid artery in their neck.
This trial tests a new medication to prevent strokes and blood clots in people with atrial fibrillation (an irregular heartbeat) who cannot safely take standard blood thinners. The drug works by blocking a different clotting factor, which may lower bleeding risks.
Hear when a new Atrial fibrillation trial opens
We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.