Ketamine plus weekly therapy for severe PTSD
Part of Mental health clinical trials.
This study tests whether adding ketamine to a structured, one-week psychological therapy program can reduce severe PTSD symptoms. It may help people who have had PTSD for a long time and still feel very affected.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You’re between 21 and 70 years old.
- You have chronic (long-lasting) PTSD for more than 1 year, and your PTSD severity is high on the clinician-rated CAPS-5 test.
- You can take part safely with ketamine—no major medical/neurologic conditions and no medicines that make ketamine unsafe.
- If you’re on certain psychiatric medicines, your doses must be stable for at least 4 weeks before starting study treatment.
- You must not have certain mental health conditions (like schizophrenia/psychosis) or recent bipolar mania/hypomania.
- You must not have recent substance use problems, serious suicide risk, or be pregnant/breastfeeding.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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