Clin2
NCT06228391Possibly a fitNot yet recruiting

Ketamine for PTSD and depression after head injury

PTSD, Post Traumatic Stress DisorderMajor Depressive DisorderTraumatic Brain Injury

Treatments studied

Part of Brain & nervous system, Injuries & trauma, Mental health clinical trials.

This study tests whether ketamine can help veterans who have both PTSD and depression after a mild to moderate traumatic brain injury. If you qualify, you would receive ketamine or a placebo, and the researchers will see if it improves your symptoms.

Summary written for real people, not researchers, by Clin2.

Phase
Phase 2
Enrollment
40 people
Ages
18 years to 75 years
Study type
Interventional

Who can take part

  • You are a veteran age 18 to 55.
  • You had a mild to moderate traumatic brain injury at least 3 months ago (not severe).
  • You have tried at least one antidepressant for depression or anxiety, but it didn't help enough.
  • You are currently taking a stable dose of an antidepressant or similar medication for at least 4 weeks.
  • You have not had ketamine treatment in the past 6 months.
  • You are not pregnant and are willing to use birth control if you can become pregnant.

View the official record on ClinicalTrials.gov

Quick eligibility check

Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.

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