Testing lenvatinib plus TACE and immunotherapy before liver surgery
Part of Cancer, Digestive system clinical trials.
This study tests whether a combination of the drug lenvatinib, a liver treatment called TACE, and the immunotherapy drug camrelizumab can shrink advanced hepatocellular carcinoma enough to make surgery (or “conversion resection”) possible. It may help some people live longer by improving the chance that the cancer can be removed.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are 18 to 75 years old.
- You have liver cancer (HCC) confirmed by scan criteria, biopsy, or fluid tests.
- You have not had cancer medicines for HCC before (except you may have had two or fewer TACE procedures).
- Your overall health score (ECOG) is 0 or 1, meaning you can do most daily activities.
- Your liver function is in the Child-Pugh A to B range, and your heart function and blood counts meet study lab requirements.
- You will need HBV/HCV tests to be controlled (if you have hepatitis B) or negative (for hepatitis C), and you must not be planning a pregnancy.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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