Clinical trials
Clostridioides Difficile Infection Recurrence clinical trials
Below are recruiting clostridioides difficile infection recurrence clinical trials, each written for real people, not researchers. We’re tracking 13 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT07513285RecruitingPhase 2
Ibezapolstat pill for recurrent C. difficile infection
This trial tests a new oral antibiotic called ibezapolstat to treat recurrent C. difficile infection (CDI)—a serious diarrheal illness caused by bacteria in your gut. The study focuses on patients who have had multiple CDI episodes and may benefit from a different treatment approach.
Sacramento, CaliforniaAges 18–90 - NCT07285213RecruitingPhase 2
Preventing C. diff return with an antibody
This study tests a new antibody (AZD5148) to prevent C. diff infection from coming back. If you have a current C. diff infection and are being treated with antibiotics, you may be able to join.
Phoenix, ArizonaAges 18 years+ - NCT05266807RecruitingPhase 3
Capsule fecal transplant to prevent C. difficile coming back
This study tests whether taking a capsule form of fecal microbiota transplant (FMT) can help adults with their first C. difficile infection—or a first relapse—get better and reduce repeat episodes. Participants also take specific antibiotics for C. difficile as part of the study process.
Basel, BaselAges 18 years+ - NCT05739825Recruiting
Fecal transplant to change gut bacteria in C. difficile infection
This trial studies whether fecal microbiota transplantation (a procedure that transfers healthy stool bacteria) can change a person’s gut bacteria after repeated C. difficile infection. It may help reduce recurring infections by restoring a healthier balance of gut microbes.
RomaAges 18–90 - NCT06030245Recruiting
Tracking recovery from C. diff infection in hospital patients
This study follows patients with Clostridioides difficile (C. diff) infection to see how their symptoms improve and when the bacteria clear from their body. It aims to better understand recovery and guide treatment.
ParisAges 18 years+ - NCT06237452RecruitingPhase 3
VE303 to prevent repeat C. diff infections
This trial tests a new medicine called VE303, a live bacterial therapy, to prevent C. diff infections from coming back. It is for people who have had C. diff at least once in the last 6 months, or who are at high risk for a repeat infection due to age or other health problems.
Huntsville, AlabamaAges 12 years+ - NCT06370884RecruitingPhase 1
Gut bacteria transplant after colon surgery
This study tests whether transplanting healthy gut bacteria into people who have had part of their colon removed can improve recovery. It may help prevent infections or other complications after surgery.
Minneapolis, MinnesotaAges 18–75 - NCT07613645Recruiting
Lifestyle changes to prevent recurring C. difficile infection
This study tests whether specific lifestyle changes during treatment for C. difficile infection (a serious gut bacteria infection) can help prevent it from coming back. You'll receive standard antibiotic treatment and follow a controlled diet while researchers track your recovery.
Ann Arbor, MichiganAges 18 years+ - NCT06692179RecruitingPhase 1
Testing a freeze-dried fecal transplant during colon surgery
This trial tests if giving a special freeze-dried mixture of healthy gut bacteria right after colon surgery is safe and possible. It may help patients recover better after the procedure.
Minneapolis, MinnesotaAges 18–75 - NCT06306014RecruitingPhase 1/Phase 2
Study of a new therapy to prevent C. diff recurrence
This study tests a new live bacteria product (EXL01) given with vancomycin to prevent C. diff from coming back. It is for people who have already had C. diff two or more times and are at high risk of another infection.
AnnecyAges 18 years+ - NCT06979609RecruitingPhase 2/Phase 3
Preventing C. diff infection with vancomycin
This trial tests whether taking vancomycin by mouth can prevent another C. diff infection when you need to take other antibiotics. It’s for patients who recently had C. diff and are about to start a new antibiotic course.
Montreal, QuebecAges 18 years+ - NCT07250724Recruiting
C. diff Toxin Levels After Antibiotic Treatment
This study looks at levels of C. diff toxins in stool after standard antibiotic treatment. It aims to understand how toxins change during recovery, which may help improve future treatments for C. diff infections.
Atlanta, GeorgiaAges 18 years+ - NCT07458984RecruitingPhase 3
Fecal transplant capsules for repeat C. diff infections
This trial tests if capsules containing fecal microbiota can prevent further Clostridioides difficile infections in people who have had at least two recurrences. If you've had multiple C. diff infections and your symptoms go away with antibiotics, this treatment might help keep them from coming back.
Helsinki, UusimaaAges 18 years+
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Common questions
- Are there clinical trials for clostridioides difficile infection recurrence?
- Yes. Clin2 currently lists 13 recruiting clostridioides difficile infection recurrence studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a clostridioides difficile infection recurrence trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a clostridioides difficile infection recurrence trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.