Metronidazole before colon cancer surgery to reduce recurrence risk
Treatments studied
Part of Cancer, Digestive system clinical trials.
This Phase 2 study tests whether taking metronidazole, an antibiotic, before surgery for colorectal cancer can improve outcomes. Participants take it before their planned operation, and doctors study the cancer tissue and related markers to see if it helps.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You’re age 18 or older and can sign informed consent
- You have newly diagnosed, untreated colon cancer (primary colorectal adenocarcinoma) that’s not involving the anal area
- Your diagnosis is confirmed by colonoscopy with a biopsy, and you can provide tissue samples for lab testing
- You are scheduled for planned surgery in time to take pre-surgery antibiotics (not emergency surgery within 14 days)
- You have not taken antibiotics in the past 6 weeks and have no allergy to metronidazole or similar medicines
- You are not currently pregnant or breastfeeding, and you can use reliable birth control during the study
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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