Metronidazole with rectal cancer treatment
Treatments studied
Part of Cancer, Digestive system clinical trials.
This trial tests adding the antibiotic metronidazole to standard pre-surgery therapy for locally advanced rectal cancer. The goal is to see if changing the bacteria in your gut can make the cancer treatment work better.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You have been diagnosed with locally advanced rectal cancer (T3, T4, or cancer in nearby lymph nodes).
- You are scheduled to receive chemotherapy and radiation before surgery (total neoadjuvant therapy).
- You have not had chemotherapy for this cancer before.
- You are at least 18 years old.
- You are in fairly good health (able to do daily activities) and your kidney, liver, and blood cell counts are adequate.
- You agree to use effective birth control during the study, if applicable.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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