Antibiotics before surgery for advanced rectal cancer
Treatments studied
Part of Cancer, Digestive system clinical trials.
This trial tests if taking antibiotics before standard treatment can improve outcomes for people with advanced rectal cancer that requires surgery.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are 18 years or older.
- You have been diagnosed with rectal adenocarcinoma (a common type of rectal cancer).
- Your tumor is in the middle or lower part of the rectum, located below a certain point seen on MRI.
- Your tumor is locally advanced, meaning it has spread nearby or is large enough that surgery to remove the rectum is needed.
- You can tolerate a full course of neoadjuvant (before surgery) treatment.
- Your tumor does not have a specific genetic instability called MSI (microsatellite instability), which is checked by a lab test.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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