Clin2
NCT05751343Possibly a fitRecruiting

Test atezolizumab and bevacizumab with liver cancer procedures

Hepatocellular Carcinoma

Part of Cancer, Digestive system clinical trials.

This Phase 2 trial tests whether atezolizumab plus bevacizumab, given along with liver cancer treatment procedures (TACE/HAIC), can help people with advanced liver cancer that cannot be removed by surgery. It mainly looks at whether these medicines can control the cancer more effectively and safely.

Summary written for real people, not researchers, by Clin2.

Phase
Phase 2
Enrollment
55 people
Ages
18 years to 75 years
Study type
Interventional

Who can take part

  • You have advanced liver cancer (HCC) that cannot be removed with surgery
  • Your liver function is fairly preserved (Child-Pugh A or B)
  • You are able to care for yourself most of the time (ECOG 0–1)
  • Your blood counts are high enough (white cells, neutrophils, platelets, and hemoglobin meet the lab cutoffs)
  • You do not have serious heart, lung, or kidney disease
  • You have no other separate (second) primary cancer, and you can take both study medicines

View the official record on ClinicalTrials.gov

Quick eligibility check

Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.

Similar studies

Other trials that look related to this one.

NCT04803994Recruiting· Phase 3
Atezolizumab plus bevacizumab versus TACE for liver cancer

This trial studies whether a combination of immune therapy (atezolizumab) and a blood-vessel-targeting drug (bevacizumab) works better than a standard procedure called TACE for people with intermediate-stage liver cancer (HCC). It may help shrink tumors and help patients live longer with fewer complications.

Graz
NCT07281664Not yet recruiting
Combination treatment for advanced liver cancer

This trial tests a combination of treatments for liver cancer that cannot be removed with surgery. It uses a procedure to block the tumor's blood supply plus two drugs that help the immune system fight the cancer. This may help shrink tumors and slow the disease.

NCT07543510Not yet recruiting
Low-dose drugs with standard local treatment for liver cancer

This trial tests giving a low dose of two drugs (bevacizumab and atezolizumab) alongside standard local treatments (TACE and HAIC) for liver cancer that cannot be removed with surgery. The goal is to see if this combination helps control the tumor better or improves outcomes.

NCT05992220Recruiting· Phase 2
Immunotherapy with or without radiation for liver cancer

This trial tests a combination of two immunotherapy drugs (atezolizumab and bevacizumab) with or without targeted radiation therapy for liver cancer that has invaded the major blood vessels of the liver. The goal is to see if adding radiation helps shrink tumors or slow the disease.

Seoul
NCT06789757Recruiting· Phase 2
Study of 3 drugs for liver cancer that can't be removed by surgery

This trial tests if combining two immunotherapy drugs (atezolizumab and bevacizumab) with a brain-health medicine (memantine) can help people with advanced liver cancer that isn't treatable with surgery. It aims to see if this triple therapy works better than standard options.

Fairfax, Virginia
NCT07192185Recruiting· Phase 2
Chemo plus immunotherapy for advanced liver cancer after first treatment fails

This trial tests a new combination of chemotherapy (FOLFOX) plus atezolizumab and bevacizumab for people with advanced liver cancer that has grown after having atezolizumab and bevacizumab alone. The goal is to see if adding chemo helps stop the cancer from growing further.

Guangzhou, Guangdong

Hear when a new Hepatocellular Carcinoma trial opens

We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.