Clin2
NCT07543510Possibly a fitNot yet recruiting

Low-dose drugs with standard local treatment for liver cancer

Hepatocellular CarcinomaAtezolizumab Plus BevacizumabTransarterial Chemoembolization

Part of Cancer, Digestive system clinical trials.

This trial tests giving a low dose of two drugs (bevacizumab and atezolizumab) alongside standard local treatments (TACE and HAIC) for liver cancer that cannot be removed with surgery. The goal is to see if this combination helps control the tumor better or improves outcomes.

Summary written for real people, not researchers, by Clin2.

Phase
N/A
Enrollment
38 people
Ages
18 years and older
Study type
Interventional

Who can take part

  • You are 18 or older.
  • You have liver cancer (hepatocellular carcinoma) that cannot be surgically removed.
  • The cancer is suitable for a treatment called TACE (chemoembolization) and HAIC (hepatic artery infusion chemotherapy).
  • You have not had any prior whole-body treatment for liver cancer.
  • Your health status is good (ECOG 0 or 1) and your liver function is at least mildly preserved (Child-Pugh class A or B7).
  • You do not have serious autoimmune disease, active infections, or recent heart or blood vessel problems.

View the official record on ClinicalTrials.gov

Quick eligibility check

Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.

Similar studies

Other trials that look related to this one.

NCT04803994Recruiting· Phase 3
Atezolizumab plus bevacizumab versus TACE for liver cancer

This trial studies whether a combination of immune therapy (atezolizumab) and a blood-vessel-targeting drug (bevacizumab) works better than a standard procedure called TACE for people with intermediate-stage liver cancer (HCC). It may help shrink tumors and help patients live longer with fewer complications.

Graz
NCT07281664Not yet recruiting
Combination treatment for advanced liver cancer

This trial tests a combination of treatments for liver cancer that cannot be removed with surgery. It uses a procedure to block the tumor's blood supply plus two drugs that help the immune system fight the cancer. This may help shrink tumors and slow the disease.

NCT05751343Recruiting· Phase 2
Test atezolizumab and bevacizumab with liver cancer procedures

This Phase 2 trial tests whether atezolizumab plus bevacizumab, given along with liver cancer treatment procedures (TACE/HAIC), can help people with advanced liver cancer that cannot be removed by surgery. It mainly looks at whether these medicines can control the cancer more effectively and safely.

Guangzhou, Guangdong
NCT06789757Recruiting· Phase 2
Study of 3 drugs for liver cancer that can't be removed by surgery

This trial tests if combining two immunotherapy drugs (atezolizumab and bevacizumab) with a brain-health medicine (memantine) can help people with advanced liver cancer that isn't treatable with surgery. It aims to see if this triple therapy works better than standard options.

Fairfax, Virginia
NCT05970666Recruiting· Phase 2
TACE plus immunotherapy and VEGF drug for unresectable liver cancer

This trial tests whether combining TACE (a liver-targeted chemo procedure) with two medicines—an immune “checkpoint” drug and a blood-vessel blocking drug—can control unresectable hepatocellular carcinoma. It’s designed for people who can’t have surgery or curative ablation, and who still have reasonably strong liver and overall health.

Xiamen, Fujian
NCT05992220Recruiting· Phase 2
Immunotherapy with or without radiation for liver cancer

This trial tests a combination of two immunotherapy drugs (atezolizumab and bevacizumab) with or without targeted radiation therapy for liver cancer that has invaded the major blood vessels of the liver. The goal is to see if adding radiation helps shrink tumors or slow the disease.

Seoul

Hear when a new Hepatocellular Carcinoma trial opens

We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.